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Last Updated: November 29, 2021

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Patent: 6,916,813

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Summary for Patent: 6,916,813
Title: (1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase
Abstract:Compounds having the formula (I), and pharmaceutically acceptable salts thereof, ##STR1## are useful for modulating mitochondrial F.sub.1 F.sub.0 ATPase activity and treating ischemic conditions including myocardial infarction, congestive heart failure, and cardiac arrhythmias.
Inventor(s): Atwal; Karnail S. (Pennington, NJ), Grover; Gary J. (Stockton, NJ), Ding; Charles Z. (Dallas, TX), Stein; Philip D. (Pennington, NJ), Lloyd; John (Yardley, PA), Ahmad; Saleem (Wall, NJ), Hamann; Lawrnce G. (Cherry Hill, NJ), Green; David (Haverhill, MA), Ferrara; Francis N. (Bedminster, NJ)
Assignee: Bristol-Myers Squibb Co. (Princeton, NJ)
Application Number:10/315,818
Patent Claims:see list of patent claims

Details for Patent 6,916,813

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 1978-01-16 ⤷  Try it Free 2021-12-10
Genentech, Inc. ACTIVASE alteplase For Injection 103172 1987-11-13 ⤷  Try it Free 2021-12-10
Genentech, Inc. CATHFLO ACTIVASE alteplase For Injection 103172 2001-09-04 ⤷  Try it Free 2021-12-10
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 1994-12-22 ⤷  Try it Free 2021-12-10
Chiesi Usa, Inc. RETAVASE reteplase For Injection 103786 1996-10-30 ⤷  Try it Free 2021-12-10
Immunex Corporation ENBREL etanercept For Injection 103795 1998-11-02 ⤷  Try it Free 2021-12-10
Immunex Corporation ENBREL etanercept For Injection 103795 1999-05-27 ⤷  Try it Free 2021-12-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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