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Last Updated: December 7, 2021

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Patent: 6,858,580

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Summary for Patent: 6,858,580
Title: Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
Abstract:A non-polydispersed mixture of conjugates in which each conjugate in the mixture comprises a drug coupled to an oligomer that includes a polyalkylene glycol moiety is disclosed. The mixture may exhibit higher in vivo activity than a polydispersed mixture of similar conjugates. The mixture may be more effective at surviving an in vitro model of intestinal digestion than polydispersed mixtures of similar conjugates. The mixture may result in less inter-subject variability than polydispersed mixtures of similar conjugates.
Inventor(s): Ekwuribe; Nnochiri N. (Cary, NC), Price; Christopher H. (Chapel Hill, NC), Ansari; Aslam M. (Rockville, MD), Odenbaugh; Amy L. (Morrisville, NC)
Assignee: Nobex Corporation (Durham, NC)
Application Number:09/873,797
Patent Claims:see list of patent claims

Details for Patent 6,858,580

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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