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Last Updated: October 26, 2021

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Patent: 6,830,923

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Summary for Patent: 6,830,923
Title: Genetics units for inhibiting the function of RNA
Abstract:The invention relates to a genetic unit, optionally present as a multiple-copy, for inhibiting RNA. The unit contains the transcription units necessary for transcription by polymerase III and a DNA coding for inhibiting RNA, which is arranged within the unit in such a way that the transcribed RNA is part of the polymerase III transcript. Using these units it is possible to achieve increased stability of the inhibiting RNA, which may occur in the form of ribozymes or antisense-RNAs, whilst maintaining an undiminished activity. The invention further relates to a process for introducing the genetic units into the cell, the use of these units and pharmaceutical preparations containing them.
Inventor(s): Beug; Hartmut (Vienna, AT), Birnstiel; Max L. (Vienna, AT), Cotten; Matthew (Vienna, AT), Wagner; Ernst (Langenzersdorf, AT), Kandolf; Harald (Vienna, AT)
Assignee: Boehringer Inglheim International GmbH (Ingelheim am Rhein, DE)
Application Number:07/947,982
Patent Claims:see list of patent claims

Details for Patent 6,830,923

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2021-12-14
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2021-12-14
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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