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Last Updated: December 2, 2020

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Patent: 6,825,208

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Summary for Patent: 6,825,208
Title: Tetrahydroquinoline derivatives as antithrombotic agents
Abstract:This invention relates generally to tetracyclic tetrahydroquinoline compounds, and analogues thereof, and pharmaceutically acceptable salt forms thereof, which are selective inhibitors of serine protease enzymes, especially factor VIIa; pharmaceutical compositions containing the same; and methods of using the same as anticoagulant agents for modulation of the coagulation cascade.
Inventor(s): Zhou; Jinglan (San Diego, CA), Robinson; Leslie (Del Mar, CA), Gubernator; Nikolaus M. (Del Mar, CA), Saiah; Eddine (LaJolla, CA), Bai; Xu (Carlsbad, CA), Gu; Xin (Scotch Plains, NJ)
Assignee: Bristol-Myers Squibb Pharma Company (Princeton, NJ)
Application Number:10/223,860
Patent Claims:see list of patent claims

Details for Patent 6,825,208

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial Bristol-Myers Squibb Pharma Company (Princeton, NJ) 2021-08-20 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Bristol-Myers Squibb Pharma Company (Princeton, NJ) 2021-08-20 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Bristol-Myers Squibb Pharma Company (Princeton, NJ) 2021-08-20 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Bristol-Myers Squibb Pharma Company (Princeton, NJ) 2021-08-20 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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