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Last Updated: November 28, 2021

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Patent: 6,800,461

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Summary for Patent: 6,800,461
Title: Modified factor VIII cDNA
Abstract:A modified Factor VIII cDNA is described in which the B-domain of the wild-type Factor VIII cDNA has been deleted and a truncated Factor IX intron 1 has been inserted in one or more locatons of the Factor VIII cDNA. Such modified Factor VIII cDNA may be used for a higher yield production of Factor VIII in vitro as well as in a transfervector for gene therapy.
Inventor(s): Negrier; Claude (Irigny, FR), Plantier; Jean Luc (Grigny, FR)
Assignee: Aventis Behring GmbH (Marburg, DE)
Application Number:09/880,887
Patent Claims:see list of patent claims

Details for Patent 6,800,461

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2019-03-17
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2019-03-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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