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Last Updated: September 28, 2020

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Patent: 6,780,614

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Summary for Patent: 6,780,614
Title: Modified factor VIII cDNA and its use for the production of factor VIII
Abstract:A modified Factor VIII cDNA is disclosed wherein the B-domain of the wild type factor cDNA has been deleted and a truncated Factor IX intron 1 has been inserted in two locations of the Factor VIII cDNA and as a promoter a cDNA is used which is suitable for the expression in hematopoietic cell lines and specifically in platelets.
Inventor(s): Negrier; Claude (Irigny, FR), Plantier; Jean-Luc (Gringy, FR)
Assignee: Aventis Behring GmbH (Marburg, DE)
Application Number:10/067,894
Patent Claims:see list of patent claims

Details for Patent 6,780,614

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Aventis Behring GmbH (Marburg, DE) 2021-02-09 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Aventis Behring GmbH (Marburg, DE) 2021-02-09 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Aventis Behring GmbH (Marburg, DE) 2021-02-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Merck
Moodys
Colorcon
Johnson and Johnson
Boehringer Ingelheim
AstraZeneca

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