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Last Updated: September 27, 2020

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Patent: 6,740,521

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Summary for Patent: 6,740,521
Title: High-sensitive detection of environmental pollutants
Abstract:The present invention provides a bioassay system, for detection of hazardous chemical substances, natural toxic substances in the environment and unknown toxic compounds, with high sensitivity, simplicity and speed. The invention provides cells and a method of using the cells for use in the bioassay system. The cell provided by the invention contains a heat shock factor binding DNA sequence and a transcriptional regulatory sequence necessary on an occasion of stress induction as a transcriptional regulatory factor binding site. The cell also possesses a reporter gene under the control of the promoter. The reporter gene is connected, on the downstream side, to the SV40pA signal without any intervening intron.
Inventor(s): Isoda; Hiroko (Tsukuba, JP), Koyama; Takashi (Yuki, JP), Tasaki; Masako (Tsukuba, JP), Oka; Syuichi (Tsukuba, JP), Sugiura; Norio (Tsuchiura, JP), Maekawa; Takaaki (Ibaraki, JP), Inamori; Yuhei (Tsukuba, JP), Yokota; Shinichi (Takasago, JP), Kitahara; Mikio (Kobe, JP), Nagata; Kazuhiro (Kyoto, JP)
Assignee: Kaneka Corporation (Osaka, JP) Agency of Industrial Science and Technology (Tokyo, JP) Ministry of International Trade and Industry (Tokyo, JP)
Application Number:10/094,151
Patent Claims:see list of patent claims

Details for Patent 6,740,521

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Kaneka Corporation (Osaka, JP) Agency of Industrial Science and Technology (Tokyo, JP) Ministry of International Trade and Industry (Tokyo, JP) 2021-09-07 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Kaneka Corporation (Osaka, JP) Agency of Industrial Science and Technology (Tokyo, JP) Ministry of International Trade and Industry (Tokyo, JP) 2021-09-07 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Kaneka Corporation (Osaka, JP) Agency of Industrial Science and Technology (Tokyo, JP) Ministry of International Trade and Industry (Tokyo, JP) 2021-09-07 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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