Luciferase reporter bioassay of parathyroid hormone compounds
This invention is directed to a bioassay for determining the functionality of parathyroid hormone compounds. More particularly, this invention is directed to a bioassay wherein the compound to be tested is added to a culture of parathyroid hormone receptor expressing cells bearing a reporter gene under the transcriptional control of multiple c-AMP responsive elements.
Labaudiniere; Richard F. (Collegeville, PA), Yu; Kin T. (Limerick, PA), Crumley; Gregg R. (Philadelphia, PA), Morse; Clarence C. (Royersford, PA)
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