Production of collagen in the milk of transgenic mammals
The invention provides transgenic nonhuman mammals capable secreting exogenous procollagen or collagen into their milk. The mammals are healthy and capable of producing procollagen or collagen at high levels, usually in trimeric form. Suitable transgenes for incorporation into the mammals are also provided.
Karatzas; Costas N. (Beaconsfield, CA), Pieper; Frank (Utrecht, NL), De Wit; Ineke (Leiden, NL), Berg; Richard (Los Altos, CA), Platenburg; Gerard (Voorschoten, NL), Toman; Paul David (Mountain View, CA)
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