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Last Updated: July 11, 2020

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Patent: 6,696,090

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Summary for Patent: 6,696,090
Title: Electro-powder
Abstract:A method and a process are disclosed for preparation of medical electro-powders. The electro-powder results from preparations of chemical and biological substances to form electro-powders suitable for electrostatic charging and dosing for functionality in a dry powder inhaler device. The electro-powder resulting from the method and process forms an active powder substance or a dry powder medical formulation with a fine particle fraction representing of the order 50% or more of the content having a size ranging between 0.5-5 .mu.m and provides electrostatic properties with an absolute specific charge per mass after charging of the order 0.1.times.10.sup.-6 to 25.times.10.sup.-6 C/g and presenting a charge decay rate constant Q.sub.50 >0.1 sec with a tap density of less than 0.8 g/ml and a water activity a.sub.w of less than 0.5. In the processing the active substance is a generally pharmaceutical active chemical or biological substance, for instance a polyeptide or any other corresponding substance selected alone or mixed or blended together with one or more excipients being a compound to improve electrostatic properties of the medical dry powder substance or dry powder medical formulation. Further the electro-powder may even be formed as a micro-encapsulation by coating micronized powder with the excipient in such a way that the active substance is capsulated, whereby the powder electrostatic properties mainly comes from the excipient.
Inventor(s): Nilsson; Thomas (Mariefred, SE), Nilsson; Lars-Gunnar (Koping, SE)
Assignee: Microdrug AG (Hergiswil, CH)
Application Number:09/636,548
Patent Claims:see list of patent claims

Details for Patent 6,696,090

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Microdrug AG (Hergiswil, CH) 2020-08-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Microdrug AG (Hergiswil, CH) 2020-08-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Microdrug AG (Hergiswil, CH) 2020-08-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Microdrug AG (Hergiswil, CH) 2020-08-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Merck
Colorcon
Boehringer Ingelheim
Baxter
Medtronic
McKesson

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