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Last Updated: September 22, 2020

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Patent: 6,692,699

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Summary for Patent: 6,692,699
Title: Biochemical blocking layer for liquid crystal assay
Abstract:A rubbed substrate structure for use in a liquid crystal assay device, includes: a biochemical blocking compound chemically immobilized on a surface of one side of a support forming a biochemical blocking layer; and a biomolecule recognition agent deposited on the side of the support containing the biochemical blocking layer. The biomolecule recognition agent includes a recognition site capable of selectively recognizing a target species to be detected by the liquid crystal assay device. Additionally, the surface of the side of the support containing the biochemical blocking layer is rubbed such that it possesses features that drive a uniform anchoring of liquid crystals when the liquid crystals contact the side of the support containing the biochemical blocking layer. A method for preparing a rubbed substrate structure for use in a liquid crystal assay device, optical cells for use in a liquid crystal assay, liquid crystal assay devices, kits for use in a liquid crystal assay, and methods for detecting the presence of a target species using a liquid crystal assay device are also disclosed.
Inventor(s): Abbott; Nicholas L. (Madison, WI), Kim; Seung-Ryeol (Madison, WI)
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Application Number:09/784,679
Patent Claims:see list of patent claims

Details for Patent 6,692,699

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Wisconsin Alumni Research Foundation (Madison, WI) 2020-02-16 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Wisconsin Alumni Research Foundation (Madison, WI) 2020-02-16 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Wisconsin Alumni Research Foundation (Madison, WI) 2020-02-16 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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