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Generated: July 20, 2019

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Patent: 6,689,566

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Summary for Patent: 6,689,566
Title: Methods, kits, and antibodies for detecting parathyroid hormone
Abstract:The present invention relates to novel methods and devices for detecting whole or non-fragmented parathyroid hormone (wPTH) in a biological sample. In particular, a novel monoclonal or polyclonal antibody or antibody fragment is used that is specific for a portion of the initial peptide sequence for wPTH which comprises a domain for adenylate cyclase activation, (amino acids 2 to 8), wherein at least four amino acids in this sequence are part of the reactive portion with the antibody. The present wPTH assay can differentiate between the complete 1 to 84 amino acid sequence form of PTH and a large but incomplete 7 to 84 amino acid sequence form of PTH that is measured by commercially available \"intact\" or I-PTH assays. Measurement of both the complete biologically active form of PTH and the large but biologically inactive form of PTH can lead to the misdiagnosis of the parathyroid function in patients.
Inventor(s): Cantor; Thomas L. (El Cajon, CA), Gao; Ping (San Diego, CA)
Assignee: Scantibodies Laboratory, Inc. (Santee, CA)
Application Number:09/231,422
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,689,566
Patent Claims:see list of patent claims

Details for Patent 6,689,566

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ➤ Try a Free Trial Scantibodies Laboratory, Inc. (Santee, CA) ➤ Try a Free Trial RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ➤ Try a Free Trial Scantibodies Laboratory, Inc. (Santee, CA) ➤ Try a Free Trial RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ➤ Try a Free Trial Scantibodies Laboratory, Inc. (Santee, CA) ➤ Try a Free Trial RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ➤ Try a Free Trial Scantibodies Laboratory, Inc. (Santee, CA) ➤ Try a Free Trial RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 6,689,566

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 0042437 Jul 20, 2000
World Intellectual Property Organization (WIPO) 2005018413 Jun 02, 2005
World Intellectual Property Organization (WIPO) 2005018413 Mar 03, 2005
United States of America 2004185536 Sep 23, 2004
United States of America 2004219598 Nov 04, 2004
United States of America 2004229281 Nov 18, 2004
United States of America 2005095631 May 05, 2005
Country Patent Number Publication Date

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