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Last Updated: June 4, 2023

Patent: 6,683,155

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Summary for Patent: 6,683,155
Title: Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
Abstract:The present invention reveals a class of novel inhibitors of metalloproteinase. For convenience, these polypeptides are referred to as \"TIMP-3\", as these polypeptides represent a new class of members of the tissue inhibitors of metalloproteinases. Also provided are DNA sequences coding for all or part of the TIMP-3s, vectors containing such DNA sequences, and host cells transformed or transfected with such vectors. In addition, methods of producing recombinant TIMP-3s, methods of treating disorders, pharmaceutical compositions including TIMP-3s and antibodies selectively binding TIMP-3s are provided.
Inventor(s): Silbiger; Scott M. (Woodland Hills, CA), Koski; Raymond A. (Old Lyme Road, CT)
Assignee: Amgen Inc. (Thousand Oaks, CA)
Application Number:08/728,160
Patent Claims:see list of patent claims

Details for Patent 6,683,155

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Bayer Healthcare Pharmaceuticals Inc. TRASYLOL aprotinin Injection 020304 12/29/1993 ⤷  Try a Trial 2013-10-06
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 01/16/1978 ⤷  Try a Trial 2013-10-06
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 06/04/1965 ⤷  Try a Trial 2013-10-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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