Patent: 6,683,155
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Summary for Patent: 6,683,155
Title: | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
Abstract: | The present invention reveals a class of novel inhibitors of metalloproteinase. For convenience, these polypeptides are referred to as \"TIMP-3\", as these polypeptides represent a new class of members of the tissue inhibitors of metalloproteinases. Also provided are DNA sequences coding for all or part of the TIMP-3s, vectors containing such DNA sequences, and host cells transformed or transfected with such vectors. In addition, methods of producing recombinant TIMP-3s, methods of treating disorders, pharmaceutical compositions including TIMP-3s and antibodies selectively binding TIMP-3s are provided. |
Inventor(s): | Silbiger; Scott M. (Woodland Hills, CA), Koski; Raymond A. (Old Lyme Road, CT) |
Assignee: | Amgen Inc. (Thousand Oaks, CA) |
Application Number: | 08/728,160 |
Patent Claims: | see list of patent claims |
Details for Patent 6,683,155
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Bayer Healthcare Pharmaceuticals Inc. | TRASYLOL | aprotinin | Injection | 020304 | 12/29/1993 | ⤷ Try a Trial | 2013-10-06 |
Microbix Biosystems Inc. | KINLYTIC | urokinase | For Injection | 021846 | 01/16/1978 | ⤷ Try a Trial | 2013-10-06 |
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Try a Trial | 2013-10-06 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |