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Last Updated: September 23, 2020

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Patent: 6,683,103

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Summary for Patent: 6,683,103
Title: Sulfonamides for treatment of endothelin-mediated disorders
Abstract:Thienylsulfonamides and their pharmaceutically acceptable derivatives, pharmaceutical compositions, articles of manufacture, combinations, lyophilized powders and methods for the treatment of endothelin diseases using these formulations and sulfonamides are provided. A process of preparing an alkali metal salt of a hydrophobic sulfonamide is provided. The process includes the step of dissolving a free sulfonamide in an organic solvent in the presence of a saturated alkali metal salt solution and recovering the formed sulfonamide salt from the organic phase.
Inventor(s): Wu; Chengde (Houston, TX), Blok; Natalie (Houston, TX), Kogan; Timothy (late of Escondido, CA), Keller; Karin (Austin, TX)
Assignee: Texas Biotechnology Corporation (Houston, TX)
Application Number:10/029,561
Patent Claims:see list of patent claims

Details for Patent 6,683,103

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Texas Biotechnology Corporation (Houston, TX) 2013-10-21 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Texas Biotechnology Corporation (Houston, TX) 2013-10-21 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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