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Last Updated: December 2, 2021

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Patent: 6,652,854

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Summary for Patent: 6,652,854
Title: Methods for treating autoimmune and chronic inflammatory conditions using antagonists of CD30 or CD30L
Abstract:The invention provides methods of treating autoimmune and chronic inflammatory conditions by administering agents that hinder the CD30/CD30L interaction, combination treatments, and methods of treating conditions resistant to treatment with TNF.alpha. inhibitors by administering agents that inhibit signal transduction by CD30 or IL-1. Included also are treatments involving concurrently administering agents that block the CD30/CD30L interaction and agents that antagonize the IL-4/IL-4R interaction. Additionally provided is an animal model for screening candidate agents for their efficacy in treating conditions that are resistant to treatment with TNF.alpha. inhibitors.
Inventor(s): Mohler; Kendall M. (Poulsbo, WA), Barone; Dauphine S. (Everett, WA), Kennedy; Mary K. (Seattle, WA)
Assignee: Immunex Corporation (Seattle, WA)
Application Number:09/921,667
Patent Claims:see list of patent claims

Details for Patent 6,652,854

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REMICADE infliximab For Injection 103772 1998-08-24 ⤷  Free Forever Trial 2020-08-08
Immunex Corporation ENBREL etanercept For Injection 103795 1998-11-02 ⤷  Free Forever Trial 2020-08-08
Immunex Corporation ENBREL etanercept For Injection 103795 1999-05-27 ⤷  Free Forever Trial 2020-08-08
Immunex Corporation ENBREL etanercept Injection 103795 2004-09-27 ⤷  Free Forever Trial 2020-08-08
Immunex Corporation ENBREL etanercept Injection 103795 2007-02-01 ⤷  Free Forever Trial 2020-08-08
Immunex Corporation ENBREL MINI etanercept Injection 103795 2017-09-14 ⤷  Free Forever Trial 2020-08-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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