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Last Updated: November 29, 2020

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Patent: 6,617,161

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Summary for Patent: 6,617,161
Title: Serum-free cell growth medium
Abstract:A chemically defined-serum free growth medium for the in vitro and ex vivo of cells and cell lines. The medium consists of about a one to one ratio (v/v) of two basal growth media containing .alpha.-ketoglutarate, insulin, transferrin, selenium, bovine serum albumin, linoleic acid, ceruloplasmin, cholesterol, phosphatidyl-ethanolamine, .alpha.-tocopherol acid succinate, reduced glutathione, taurine, triiodothyronine, hydrocortisone, parathyroid hormone, L-ascorbic acid 2-sulfate, .beta.-glycerophosphate, PDGF, EGF and FGF. Chondrocytes, when cultured in this medium in the presence of a cartilage derived morphogenetic protein or bone morphogenetic protein, retain their cartilaginous phenotype.
Inventor(s): Luyten; Frank P. (Kraainem, BE), Erlacher; Ludwig (Vienna, AT)
Assignee: The United States of America as represented by the Department of Health and Human Services (Washington, DC)
Application Number:09/851,921
Patent Claims:see list of patent claims

Details for Patent 6,617,161

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) 2019-12-21 RX search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) 2019-12-21 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) 2019-12-21 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) 2019-12-21 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial The United States of America as represented by the Department of Health and Human Services (Washington, DC) 2019-12-21 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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