Upgrade for Complete Access See Plans and Pricing

Serving leading biopharmaceutical companies globally:

Express Scripts
Harvard Business School
Johnson and Johnson

Last Updated: December 7, 2021

DrugPatentWatch Database Preview

Patent: 6,604,698

➤ Subscribe for complete access

« Back to Dashboard

Summary for Patent: 6,604,698
Title: Media milling
Abstract:This invention describes a process for preparing a dispersion of solid particles of a milled substrate in a fluid carrier comprising the steps of (a) providing a plurality of large size milling media to the milling chamber of a media mill and forming a depth filter therefrom on an exit screen or separator in the milling chamber; (b) adding to said milling chamber a plurality of small size milling media optionally containing additional large size milling media, a conglomerate of a solid substance comprising a substrate to be milled and optionally one or more than one surface active substance, and a fluid carrier; (c) milling said conglomerate in said milling chamber to produce very small milled substrate product particles; and (d) separating said milled substrate particles suspended in said fluid carrier from the media through said depth filter; wherein the exit screen comprises openings of size S.sub.0 ; the large size media have a size distribution S.sub.1 of which all are larger than S.sub.0 ; the small size media have a size distribution S.sub.2 which are smaller than S.sub.0 ; the very small milled substrate particles have a size distribution S.sub.3 and are smaller than all of the small media; and the large size media and the small size media are essentially retained in the milling chamber.
Inventor(s): Verhoff; Frank H. (Cincinnati, OH), Snow; Robert A. (West Chester, PA), Pace; Gary W. (Raleigh, NC)
Assignee: SkyePharma Canada, Inc. (Montreal, CA)
Application Number:09/852,054
Patent Claims:see list of patent claims

Details for Patent 6,604,698

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1987-06-23 ⤷  Try it Free 2020-05-10
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1986-10-16 ⤷  Try it Free 2020-05-10
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 1999-02-04 ⤷  Try it Free 2020-05-10
Emd Serono, Inc. SAIZEN somatropin For Injection 019764 1996-10-08 ⤷  Try it Free 2020-05-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Harvard Business School
Express Scripts
Johnson and Johnson

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.