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Last Updated: April 25, 2024

Patent: 6,572,856

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Summary for Patent: 6,572,856

Title:	Methods for the prevention and treatment of cancer using anti-C3b(i) antibodies
Abstract:	The present invention relates to the treatment and prevention of cancer, viral infections and microbial infections by the administration of anti-C3b(i) antibodies. The present invention also relates to methods of treating and preventing cancer, viral infection, or microbial infection in an animal comprising administering to said animal IgG antibodies, IgM antibodies and/or complement components in combination with antibodies specific for C3b(i). The present invention also relates methods of treating and preventing cancer, viral infection or microbial infection in an animal comprising administrating said animal antibodies that immunospecifically bind to one or more cancer cell antigens, viral antigens or microbial antigens, respectively, in combination with antibodies immunospecific for C3b(i). The present invention further relates to the detection, imaging, diagnosis and monitoring of cancer utilizing C3b(i) specific antibodies.
Inventor(s):	Taylor; Ronald (Charlottesville, VA), Nardin; Alessandra (Paris, FR), Sutherland; William M. (Earlysville, VA), Sokoloff; Mitchell H. (Hinsdale, IL), Chung; Leland (Lovingston, VA)
Assignee:	The University of Virginia Patent Foundation (Charlottesville, VA)
Application Number:	09/724,620
Patent Claims:	see list of patent claims

Details for Patent 6,572,856

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	⤷ Try a Trial	2018-09-10
Idec Pharmaceuticals Corp.	RITUXAN	rituximab	Injection	103737	02/19/2002	⤷ Try a Trial	2018-09-10
Genentech, Inc.	RITUXAN HYCELA	rituximab and hyaluronidase human	Injection	761064	06/22/2017	⤷ Try a Trial	2018-09-10
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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