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Generated: September 23, 2019

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Patent: 6,565,879

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Summary for Patent: 6,565,879
Title: Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
Abstract:A method is provided for increasing the permeability of skin or mucosal tissue to a topically or transdermally administered pharmacologically or cosmeceutically active peptide, polypeptide or protein. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the peptide, polypeptide or protein through a body surface while minimizing the likelihood of skin damage, irritation or sensitization. Formulations and drug delivery devices employing hydroxide-releasing agents as permeation enhancers are provided as well.
Inventor(s): Luo; Eric C. (Plano, TX), Jacobson; Eric C. (San Diego, CA), Hsu; Tsung-Min (San Diego, CA)
Assignee: Dermatrends, Inc. (San Diego, CA)
Application Number:09/687,937
Patent Claims:see list of patent claims

Details for Patent 6,565,879

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Sign Up Dermatrends, Inc. (San Diego, CA) 2019-12-16 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13 ➤ Sign Up Dermatrends, Inc. (San Diego, CA) 2019-12-16 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13 ➤ Sign Up Dermatrends, Inc. (San Diego, CA) 2019-12-16 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13 ➤ Sign Up Dermatrends, Inc. (San Diego, CA) 2019-12-16 RX search
Amgen NEUPOGEN filgrastim VIAL 103353 001 1991-02-20 ➤ Sign Up Dermatrends, Inc. (San Diego, CA) 2019-12-16 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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