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Last Updated: August 11, 2020

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Patent: 6,565,844

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Summary for Patent: 6,565,844
Title: Protein production and protein delivery
Abstract:The present invention relates to DNA constructs that alter the expression of a targeted gene in a cell when the DNA construct is homologously recombined with a target site within the chromosomal DNA of the cell, as well as to a cell into which has been incorporated a new transcription unit containing an exogenous regulatory sequence operatively linked to an endogenous gene of the cell\'s chromosomal DNA. These constructs and cells can be used in a method of altering expression of the targeted gene.
Inventor(s): Treco; Douglas (Arlington, MA), Heartlein; Michael W. (Boxborough, MA), Selden; Richard F (Wellesley, MA)
Assignee: Transkaryotic Therapies, Inc. (Cambridge, MA)
Application Number:09/312,245
Patent Claims:see list of patent claims

Details for Patent 6,565,844

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Transkaryotic Therapies, Inc. (Cambridge, MA) 2011-11-05 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Transkaryotic Therapies, Inc. (Cambridge, MA) 2011-11-05 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Transkaryotic Therapies, Inc. (Cambridge, MA) 2011-11-05 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Transkaryotic Therapies, Inc. (Cambridge, MA) 2011-11-05 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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