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Last Updated: September 30, 2020

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Patent: 6,555,542

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Summary for Patent: 6,555,542
Title: Sulfonamide lactam inhibitors of FXa and method
Abstract:Sulfonamide lactams of the following formula ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.4a, R.sup.5, R.sup.5a, R.sup.6, R.sup.6a, R.sup.7 and R.sup.8 are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses.
Inventor(s): O\'Connor; Stephen P. (Newtown, PA), Lawrence; Michael (Yardley, PA), Shi; Yan (Flourtown, PA), Stein; Philip D. (Pennington, NJ)
Assignee: Bristol-Myers Squibb Company (Princeton, NJ)
Application Number:10/059,621
Patent Claims:see list of patent claims

Details for Patent 6,555,542

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 DISCN search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial Bristol-Myers Squibb Company (Princeton, NJ) 2021-01-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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