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Last Updated: September 21, 2020

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Patent: 6,555,377

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Summary for Patent: 6,555,377
Title: Process for production of mammalian cell lines
Abstract:Described is a process for generating a mammalian cell line from primary mammalian cells, comprising the step of: a) pre-treating a culture of said primary mammalian cells or a suspension thereof with at least one glucocorticoid, b) optional step comprising obtaining a suspension of said pre-treated culture of step a), c) transferring into the pre-treated cells of the suspension of step a) or b) at least one nucleic acid vector which is not of retroviral origin and which is competent to immortalize said pre-treated cells and d) culturing the transferred cells of step c). Furthermore, mammalian cell lines and cells obtainable by the described process are provided as well as pharmaceutical and diagnostic compositions containing such cells.
Inventor(s): Braun; Serge (Dorlisheim, FR), Perraud; Frederic (Geudertheim, FR)
Assignee: Transgene S.A. (Strasbourg, FR)
Application Number:09/559,782
Patent Claims:see list of patent claims

Details for Patent 6,555,377

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 001 2004-12-21   Start Trial Transgene S.A. (Strasbourg, FR) 2019-04-27 RX search
Bausch And Lomb VITRASE hyaluronidase INJECTABLE;INJECTION 021640 002 2004-12-21   Start Trial Transgene S.A. (Strasbourg, FR) 2019-04-27 RX search
Amphastar Pharm AMPHADASE hyaluronidase INJECTABLE;INJECTION 021665 001 2005-11-03   Start Trial Transgene S.A. (Strasbourg, FR) 2019-04-27 RX search
Akorn Inc HYDASE hyaluronidase INJECTABLE;INJECTION 021716 001 2005-10-25   Start Trial Transgene S.A. (Strasbourg, FR) 2019-04-27 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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