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Last Updated: December 5, 2021

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Patent: 6,521,449

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Summary for Patent: 6,521,449
Title: Gene construct and its use
Abstract:Compositions of matter and methods for expressing a polypeptide are provided. In one aspect, a gene construct is provided that comprises an enhancer comprising particular elements or combinations of elements from the immunoglobulin .kappa. locus, the immunoglobulin heavy chain .mu. locus, and the immunoglobulin .lambda. locus, and a promoter and polyadenylation site linked to a nucleotide sequence encoding a polypeptide from a select group. Cells comprising the gene construct, processes for producing such cells, and processes for producing the polypeptide encoded by the gene construct from such cells are also provided.
Inventor(s): Polack; Axel (Munchen, DE), Hortnagel; Konstanze (Munchen, DE), Wolf; Jurgen (Koln, DE), Mucke; Susanne (Koln, DE)
Assignee: GSF-Forschungszentrum fur Umwelt und Gesundheit GmbH (DE)
Application Number:09/434,574
Patent Claims:see list of patent claims

Details for Patent 6,521,449

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2015-11-07
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2015-11-07
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Harvard Business School

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