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Last Updated: October 1, 2020

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Patent: 6,503,713

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Summary for Patent: 6,503,713
Title: Methods for identifying RNA binding compounds
Abstract:The present invention relates to methods of screening for compounds that bind RNA molecules. In particular, the methods of the invention comprise screening a library of test compounds, each of which is attached to a solid support, with a dye-labeled RNA molecule to form a dye-labeled target RNA:support-attached test compound complex. By virtue of the dye label on the target RNA, the support becomes labeled and can be separated from unlabeled solid supports. The present invention further relates to methods of inhibiting an RNA-protein interaction, to methods of screening for compounds that increase or decrease the production of a protein, and to methods of screening for a compound that is capable of treating or preventing a disease whose progression is associated with an in vivo binding of a test compound to a target RNA.
Inventor(s): Rana; Tariq M (Piscataway, NJ)
Assignee: University of Medicine and Dentistry of New Jersey (New Brunswick, NJ)
Application Number:09/679,451
Patent Claims:see list of patent claims

Details for Patent 6,503,713

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial University of Medicine and Dentistry of New Jersey (New Brunswick, NJ) 2019-10-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial University of Medicine and Dentistry of New Jersey (New Brunswick, NJ) 2019-10-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial University of Medicine and Dentistry of New Jersey (New Brunswick, NJ) 2019-10-04 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial University of Medicine and Dentistry of New Jersey (New Brunswick, NJ) 2019-10-04 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 6,503,713

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