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Last Updated: September 30, 2020

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Patent: 6,495,155

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Summary for Patent: 6,495,155
Title: Injectable opioid partial agonist or opioid antagonist microparticle compositions and their use in reducing consumption of abused substances
Abstract:An injectable slow-release partial opioid agonist or opioid antagonist formulation is provided comprising a partial opioid agonist or opioid antagonist in a poly(D,L-lactide) excipient with a small amount of residual ethyl acetate. Upon intramuscular injection of the composition, a partial opioid agonist or opioid antagonist is released in a controlled manner over an extended period of time. The composition finds use in the treatment of heroin addicts and alcoholics to reduce consumption of the abused substances. Of particular interest are the drugs buprenorphine, methadone and naltrexone.
Inventor(s): Tice; Thomas R. (Birmingham, AL), Staas; Jay K. (Alabaster, AL), Ferrell; Teresa M. (Vestavia Hills, AL), Markland; Peter (Birmingham, AL)
Assignee: Southern Research Institute (Birmingham, AL)
Application Number:09/648,255
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,495,155
Patent Claims:see list of patent claims

Details for Patent 6,495,155

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Southern Research Institute (Birmingham, AL) 2019-08-27 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Southern Research Institute (Birmingham, AL) 2019-08-27 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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