Patent: 6,482,810
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Summary for Patent: 6,482,810
Title: | Antibiotic composition for inhibition of angiogenesis |
Abstract: | Pharmaceutical compositions for delivering an effective dose of an angiogenesis inhibitor consisting of a tetracycline or tetracycline such as minocycline. The effective dosage for inhibition of angiogenesis based on in vitro testing is between one and 500 micromolar. The compositions are delivered topically, locally or systemically using implants or injection. The composition is extremely selective for growth of endothelial cells, inhibiting growth, but is not cytotoxic at the effective dosages. |
Inventor(s): | Brem; Henry (Lutherville, MD), Tamargo; Rafael J. (Baltimore, MD), Bok; Robert A. (Minneapolis, MN) |
Assignee: | |
Application Number: | 08/227,100 |
Patent Claims: | see list of patent claims |
Details for Patent 6,482,810
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
---|---|---|---|---|---|---|---|
Smith & Nephew, Inc. | SANTYL | collagenase | Ointment | 101995 | 06/04/1965 | ⤷ Sign Up | 2019-11-19 |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |