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Last Updated: September 26, 2020

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Patent: 6,482,810

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Summary for Patent: 6,482,810
Title: Antibiotic composition for inhibition of angiogenesis
Abstract:Pharmaceutical compositions for delivering an effective dose of an angiogenesis inhibitor consisting of a tetracycline or tetracycline such as minocycline. The effective dosage for inhibition of angiogenesis based on in vitro testing is between one and 500 micromolar. The compositions are delivered topically, locally or systemically using implants or injection. The composition is extremely selective for growth of endothelial cells, inhibiting growth, but is not cytotoxic at the effective dosages.
Inventor(s): Brem; Henry (Lutherville, MD), Tamargo; Rafael J. (Baltimore, MD), Bok; Robert A. (Minneapolis, MN)
Application Number:08/227,100
Patent Claims:see list of patent claims

Details for Patent 6,482,810

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial 2019-11-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Express Scripts
Johnson and Johnson

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