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Last Updated: September 22, 2020

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Patent: 6,472,515

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Summary for Patent: 6,472,515
Title: Response element
Abstract:The present invention is directed to a novel Afx response element comprising the nucleotide sequence AACATGTT, said nucleotide sequence having a DNA binding site for the human fork head transkription factor Afx. The invention also relates to the use of the Afx response element in the screening for genes as diabetes drug targets and in the bioinformatic analysis of the human genome, said genes in turn being useful in other screening methods for compounds modifying the insulin receptor signaling pathway. A further aspect of the invention is a vector construct comprising the novel nucleotide sequence, a host cell transformed with said vector construct as well as the fusion protein expressed by said host cell.
Inventor(s): Climent-Johansson; Isabel (Stockholm, SE), Dahlman-Wright; Karin (Bromma, SE), Lake; Staffan (Lidingo, SE), Wasserman; Wyeth (Stockholm, SE)
Assignee: Biovitrum AB (Stockholm, SE)
Application Number:09/645,629
Patent Claims:see list of patent claims

Details for Patent 6,472,515

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Biovitrum AB (Stockholm, SE) 2019-08-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Biovitrum AB (Stockholm, SE) 2019-08-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Biovitrum AB (Stockholm, SE) 2019-08-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

McKesson
Colorcon
AstraZeneca
Medtronic
McKinsey
Mallinckrodt

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