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Last Updated: October 1, 2020

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Patent: 6,472,162

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Summary for Patent: 6,472,162
Title: Method for preparing thrombin for use in a biological glue
Abstract:A sterile method for preparing stable thrombin component from a single donor\'s plasma in which the thrombin component and the clotting and adhesive proteins component are harvested simultaneously from the same donor plasma in less than one hour. The combined components provide an improved biological hemostatic agent and tissue sealant by virtue of its freedom from the risk of contaminating viruses or bacteria from allogenic human or bovine blood sources. The thrombin provides polymerization of the clotting and adhesive proteins in less than five seconds, and is sufficiently stable to provide that fast clotting over a six hour period. Further, the clotting times can be predictably lengthened by diluting the thrombin with saline.
Inventor(s): Coelho; Philip Henry (El Dorado Hills, CA), Kingsley; Phil (Sacramento, CA), Brausch; Jim (Sacramento, CA), Godsey; James H. (Folsom, CA), Rock; Gail (Ottawa, CA), Madsen; Trista K. (Elk Grove, CA), Frausto; Sona B. (Sacramento, CA)
Assignee: ThermoGenesis Corp. (Rancho Cordovo, CA)
Application Number:09/328,350
Patent Claims:see list of patent claims

Details for Patent 6,472,162

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial ThermoGenesis Corp. (Rancho Cordovo, CA) 2039-09-23 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial ThermoGenesis Corp. (Rancho Cordovo, CA) 2039-09-23 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Medtronic

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