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Last Updated: September 28, 2020

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Patent: 6,458,581

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Summary for Patent: 6,458,581
Title: Process for the in vitro culture of different stages of tissue parasites
Abstract:The present invention provides a method for carrying out in vitro the complete developmental sequence culture of tissular parasites, which includes culturing the parasites in a totally defined culture medium which is an axenic monophasic liquid culture medium, free of serum and free of serum-derived or cell-derived macromolecules, proteins and peptides. For obtaining amastigote forms, this medium is buffered at a pH of 5.5 to 6.5 and has an osmolarity of at least 400 milliosmoles/kg of liquid. For obtaining promastigote forms, the medium is buffered at a pH of 7 to 7.5 and has an osmolarity of at least 300 milliosmoles/kg liquid. Application to the in vitro culture of different stages of tissular parasites such as Leishmania, T. cruzi, and hamatoprotozoa is also provided.
Inventor(s): Lemesre; Jean-Loup (Saint Martin de Londres, FR)
Assignee: Institut francais de recherche scientifique pour le developpement en (N/A) (Paris, FR)
Application Number:08/549,677
Patent Claims:see list of patent claims

Details for Patent 6,458,581

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Recordati Rare Diseases, Inc. PANHEMATIN hemin POWDER, FOR SOLUTION 101246 1 1983-07-20   Start Trial Institut francais de recherche scientifique pour le developpement en (N/A) (Paris, FR) 2013-05-13 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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