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Last Updated: September 24, 2020

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Patent: 6,420,119

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Summary for Patent: 6,420,119
Title: Methods of diagnosing and treating urinary incontinence relating to collagen proteolysis in pelvic supporting tissue
Abstract:Methods are disclosed for diagnosing urinary incontinence or a predisposition to urinary incontinence in a subject by determining the ratio of expression levels of MMPs/TIMPs in pelvic supporting tissue of the subject and comparing the ratio to a predetermined indicator. A diagnostic kit is also disclosed. Methods are disclosed for treating urinary incontinence by reducing proteolysis of collagen in pelvic supporting tissue of the subject and for identifying therapeutic agents in in vitro screens.
Inventor(s): Polan; Mary Lake (Palo Alto, CA), Chen; Bertha (Menlo Park, CA)
Assignee: The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, CA)
Application Number:09/689,291
Patent Claims:see list of patent claims

Details for Patent 6,420,119

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial The Board of Trustees of the Leland Stanford Jr. University (Palo Alto, CA) 2019-10-12 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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