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Last Updated: August 11, 2020

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Patent: 6,416,758

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Summary for Patent: 6,416,758
Title: Antibody conjugate kits for selectively inhibiting VEGF
Abstract:Disclosed are antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor regression, and yet have improved safety due to their specificity. The present invention thus provides new antibody-based compositions, methods and combined protocols for treating cancer and other angiogenic diseases. Advantageous immunoconjugate and prodrug compositions.
Inventor(s): Thorpe; Philip E. (Dallas, TX), Brekken; Rolf A. (Seattle, WA)
Assignee: Board of Regents, The University of Texax System (Austin, TX)
Application Number:09/561,526
Patent Claims:see list of patent claims

Details for Patent 6,416,758

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Board of Regents, The University of Texax System (Austin, TX) 2019-04-28 RX search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Board of Regents, The University of Texax System (Austin, TX) 2019-04-28 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Board of Regents, The University of Texax System (Austin, TX) 2019-04-28 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Board of Regents, The University of Texax System (Austin, TX) 2019-04-28 DISCN search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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