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Last Updated: December 11, 2019

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Patent: 6,403,381

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Summary for Patent: 6,403,381
Title: Inhibition of coagulation in blood and blood products
Abstract:The present invention provides methods for inhibiting blood clotting. In general, the methods include adding corn trypsin inhibitor (CTI) to blood or a blood product in an amount sufficient to inhibit the clotting. The CTI can be used alone or in combination with other anti-coagulants. In one aspect, the invention features plasma clotting assays featuring substantially prolonged clotting times. Clotting assays using whole or minimally altered blood are also provided. Further provided are methods for storing blood or blood products at low temperature with the CTI.
Inventor(s): Mann; Kenneth G. (Grand Isle, VT), Rand; Mathew D. (Danvers, MA), Cawthern; Kevin M. (Haverstraw, NY)
Assignee: University of Vermont and State Agriculture College (Burlington, VT)
Application Number:09/327,806
Patent Claims:see list of patent claims

Details for Patent 6,403,381

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REOPRO abciximab INJECTABLE; INJECTION 103575 001 1994-12-22   Start Trial University of Vermont and State Agriculture College (Burlington, VT) 2018-06-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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