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Last Updated: March 28, 2024

Patent: 6,403,381


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Summary for Patent: 6,403,381
Title: Inhibition of coagulation in blood and blood products
Abstract:The present invention provides methods for inhibiting blood clotting. In general, the methods include adding corn trypsin inhibitor (CTI) to blood or a blood product in an amount sufficient to inhibit the clotting. The CTI can be used alone or in combination with other anti-coagulants. In one aspect, the invention features plasma clotting assays featuring substantially prolonged clotting times. Clotting assays using whole or minimally altered blood are also provided. Further provided are methods for storing blood or blood products at low temperature with the CTI.
Inventor(s): Mann; Kenneth G. (Grand Isle, VT), Rand; Mathew D. (Danvers, MA), Cawthern; Kevin M. (Haverstraw, NY)
Assignee: University of Vermont and State Agriculture College (Burlington, VT)
Application Number:09/327,806
Patent Claims:see list of patent claims

Details for Patent 6,403,381

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. REOPRO abciximab Injection 103575 12/22/1994 ⤷  Try a Trial 2018-06-08
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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