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Last Updated: December 3, 2021

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Patent: 6,391,633

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Summary for Patent: 6,391,633
Title: Production of erythropoietin by endogenous gene activation
Abstract:The invention relates to human cells which are capable, on the basis of an activation of the endogenous human EPO gene, of producing EPO in a sufficient amount and purity to make possible a cost-effective production of human EPO as a pharmaceutical preparation. The invention furthermore relates to a method for the preparation of such human EPO-producing cells, DNA constructs for the activation of the endogenous EPO inhuman cells, and a method for the large technical production of EPO in human cells.
Inventor(s): Stern; Anne (Penzberg, DE), Brandt; Michael (Iffeldorf, DE), Honold; Konrad (Penzberg, DE), Auer; Johannes (Penzberg, DE), Koll; Hans (Weilheim, DE)
Assignee: Roche Diagnostics GmbH (Mannheim, DE)
Application Number:09/463,380
Patent Claims:see list of patent claims

Details for Patent 6,391,633

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2017-07-23
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2017-07-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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