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Last Updated: September 27, 2020

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Patent: 6,387,711

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Summary for Patent: 6,387,711
Title: Liquid intact parathyroid hormone (PTH) standards
Abstract:A solution of a non-reconstituted hormone and a preservative having a useful shelf life of at least six months, and, in some circumstances, at least a year. A series of solution of varying levels of the non-reconstituted hormone may be in a test kit and used in a process to determine the level of the hormone in a patient sample. In an aspect of the invention, the hormone is parathyroid hormone. The preservatives may be polyvinyl alcohol, a dissolved EDTA salt, or dissolved sodium molybdate. The hormone may be in an aqueous or a buffered matrix containing very little protein and substantial amounts of TX100 to reduce non-specific binding. The solution is incubated with a solid phase coated with an anti-hormone antibody and a labeled hormone antibody. The solid phase is read using a suitable device for measuring the labeled hormone antibody. An example of a labeled hormone antibody is an acridinium labeled hormone antibody that is read using a light reading device.
Inventor(s): Sundaram; Lata (Laguna Niguel, CA), Hoang; Ann (Lake Forest, CA), Shimizu; Stan (Trabuco Canyon, CA)
Assignee: Quest Diagnostics Investments Incorporated (Wilmington, DE)
Application Number:09/637,649
Patent Claims:see list of patent claims

Details for Patent 6,387,711

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Quest Diagnostics Investments Incorporated (Wilmington, DE) 2039-03-29 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Quest Diagnostics Investments Incorporated (Wilmington, DE) 2039-03-29 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Quest Diagnostics Investments Incorporated (Wilmington, DE) 2039-03-29 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Quest Diagnostics Investments Incorporated (Wilmington, DE) 2039-03-29 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

Moodys
Colorcon
Baxter
AstraZeneca
Boehringer Ingelheim
Merck

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