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Last Updated: October 1, 2020

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Patent: 6,365,405

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Summary for Patent: 6,365,405
Title: Compositions of chondrocytes, preparation and utilization
Abstract:This invention concerns compositions of chondrocytic cells, notably human ones, and the methods for preparing and using them. More specifically, the invention describes the production of autologous human chondrocyte suspensions, employing recombinant enzymes and/or media that are compatible with pharmaceutical use. The invention also describes methods and compositions for freezing chondrocytes, notably in the absence of DMSO. The chondrocytes which are produced can be used in vivo to restore affected cartilaginous structures, such as in post-traumatic cartilaginous defects or dissecting osteochondrite of the knee or, more generally, for treating and repairing clinically significant defects in cartilage, notably in joint cartilage.
Inventor(s): Salzmann; Jean-Loup (Paris, FR), Crespo; Andres (Ormesson sur Marne, FR), Klatzmann; David (Paris, FR), Passuti; Norbert (Saint Sebastien sur Loire, FR)
Assignee: Universite Pierre et Marie Curie (Paris IV) (Paris, Cedex, FR)
Application Number:09/662,469
Patent Claims:see list of patent claims

Details for Patent 6,365,405

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Universite Pierre et Marie Curie (Paris IV) (Paris, Cedex, FR) 2019-09-16 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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