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Last Updated: December 3, 2021

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Patent: 6,344,600

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Summary for Patent: 6,344,600
Title: Method for producing human hemoglobin proteins using plant cells
Abstract:A method for producing human hemoglobin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of a human hemoglobin protein capable of reversibly binding oxygen, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the human hemoglobin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying the human hemoglobin protein that includes a complex consisting of the protein or proteins coded for by the nucleic acid and at least one iron-containing polphyritic nucleus, or a plurality of such complexes.
Inventor(s): Merot; Bertrand (Volvic, FR), Dieryck; Wilfrid (Saint-Pathus, FR), Lenee; Philippe (Noumea, FR), Marden; Michael (Aulnay-sous-Bois, FR), Gruber; Veronique (Chamalieres, FR), Pagnier; Renee-Josee (Le Kremlin-Bicetre, FR), Baudino; Sylvie (Orcines, FR), Poyart; Claude (Paris, FR)
Assignee: Meristem Therapeutics (Clermont-Ferrand, FR) Institut National de la Sante et de la Recherche Medicale (Paris Cedex, FR)
Application Number:08/983,564
Patent Claims:see list of patent claims

Details for Patent 6,344,600

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2015-07-17
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2015-07-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Express Scripts

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