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Last Updated: September 27, 2020

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Patent: 6,288,032

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Summary for Patent: 6,288,032
Title: Osteoprotegerin
Abstract:The present invention discloses a novel secreted polypeptide, termed Osteoprotegerin, which is a member of the tumor necrosis factor receptor super family and is involved in the regulation of bone metabolism. Also disclosed are nucleic acids encoding Osteoprotegerin, polypeptides, recombinant vectors and host cells for expression, antibodies which bind Osteoprotegerin, and pharmaceutical compositions. The polypeptides are used to treat bone diseases characterized by increased resorption such as osteoporosis.
Inventor(s): Boyle; William J. (Moorpark, CA), Lacey; David L. (Thousand Oaks, CA), Calzone; Frank J. (Westlake Village, CA), Chang; Ming-Shi (Newbury Park, CA)
Assignee: Amgen Inc. (Thousand Oaks, CA)
Application Number:08/795,446
Patent Claims:see list of patent claims

Details for Patent 6,288,032

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Amgen Inc. (Thousand Oaks, CA) 2015-12-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Amgen Inc. (Thousand Oaks, CA) 2015-12-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Amgen Inc. (Thousand Oaks, CA) 2015-12-22 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Amgen Inc. (Thousand Oaks, CA) 2015-12-22 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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