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Last Updated: September 20, 2020

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Patent: 6,265,204

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Summary for Patent: 6,265,204
Title: DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
Abstract:The invention includes novel fusion nucleic acids encoding fusion polypeptides which when expressed in a filamentous fungus result in the expression of fusion polypeptides. The fusion nucleic acids comprise four nucleic acids which encode a fusion polypeptide comprising first, second, third and fourth amino acid sequences. The first nucleic acid encodes a signal polypeptide functional as a secretory sequence in a first filamentous fungus. The second nucleic acid encodes a secreted polypeptide or functional portion thereof which is normally secreted from the same filamentous fungus or a second filamentous fungus. The third nucleic acid encodes a cleavable linker while the fourth nucleic acid comprises at least two nucleic acids encoding desired polypeptides.
Inventor(s): Ward; Michael (San Francisco, CA), Power; Scott D. (San Bruno, CA)
Assignee: Genencor International, Inc. (Rochester, NY)
Application Number:08/785,668
Patent Claims:see list of patent claims

Details for Patent 6,265,204

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Genencor International, Inc. (Rochester, NY) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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