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Last Updated: September 24, 2020

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Patent: 6,258,529

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Summary for Patent: 6,258,529
Title: PCR amplification of rearranged genomic variable regions of immunoglobulin genes
Abstract:The invention features methods for isolating immunoglobulin variable region genes, and the use of these genes in the production of chimeric and isotype switched antibodies. The invention also features substantially pure DNA encoding a variable region of the antibody produced by hybridoma cell line HNK-20, and chimeric antibodies containing this variable region.
Inventor(s): Berdoz; Jose (La Tour-de-Peilz, CH), Kraehenbuhl; Jean-Pierre (Rivaz, CH)
Assignee: OraVax, Inc. (Cambridge, MA)
Application Number:08/348,548
Patent Claims:see list of patent claims

Details for Patent 6,258,529

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial OraVax, Inc. (Cambridge, MA) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial OraVax, Inc. (Cambridge, MA) 2039-02-26 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial OraVax, Inc. (Cambridge, MA) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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