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Last Updated: December 3, 2021

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Patent: 6,231,851

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Summary for Patent: 6,231,851
Title: Methods and compositions for the dry powder formulation of interferons
Abstract:According to the present invention, methods and compositions are provided for spray-dried, interferon-based dry powder compositions, particularly interferon-beta. The compositions are useful for treating conditions in humans that are responsive to treatment with interferons. In particular, the methods of the present invention rely on spray drying to produce stable, high-potency dry powder formulations of interferons, including but not limited to IFN-beta. Surprisingly, it has been found that IFN can be prepared in high potency, dry powder formulations by spray drying. Such dry powder formulations find particular utility in the pulmonary delivery of IFN.
Inventor(s): Platz; Robert M. (Half Moon Bay, CA), Kimura; Shigenobu (Ako-gun, JP), Satoh; Yu-ichiro (Kita-ku, JP), Foster; Linda C. (Mountain View, CA)
Assignee: Inhale Therapeutic Systems (San Carlos, CA)
Application Number:08/737,724
Patent Claims:see list of patent claims

Details for Patent 6,231,851

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Grifols Therapeutics Llc ALBUKED, PLASBUMIN-20, PLASBUMIN-25, PLASBUMIN-5 albumin (human) For Injection 101138 1942-10-21 ⤷  Try it Free 2014-05-18
Baxalta Us Inc. BUMINATE, FLEXBUMIN albumin (human) Injection 101452 1954-03-03 ⤷  Try it Free 2014-05-18
Csl Behring Ag ALBURX albumin (human) Injection 102366 1976-07-23 ⤷  Try it Free 2014-05-18
Grifols Biologicals Llc ALBUTEIN albumin (human) Injection 102478 1978-08-15 ⤷  Try it Free 2014-05-18
Instituto Grifols, S.a. HUMAN ALBUMIN GRIFOLS albumin (human) Injection 103352 1995-02-17 ⤷  Try it Free 2014-05-18
Instituto Grifols, S.a. HUMAN ALBUMIN GRIFOLS albumin (human) Injection 103352 2003-06-11 ⤷  Try it Free 2014-05-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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