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Last Updated: September 26, 2020

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Patent: 6,218,166

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Summary for Patent: 6,218,166
Title: Adjuvant incorporation into antigen carrying cells: compositions and methods
Abstract:Disclosed are compositions and methods for enhancing the antibody and T cell response to cellular antigens by incorporating an immunopotentiating agent into the cellular membrane or into an intracellular compartment. Such adjuvant-incorporated cell compositions are useful in methods to increase immune responses against antigens, including immunologically cryptic tumor cell antigens, and may be employed to generate useful diagnostic antibodies, to elicit anti-tumor effects in immunized animals, and to significantly prolong survival in animals with cancer.
Inventor(s): Ravindranath; Mepur H. (Los Angeles, CA), Morton; Donald L. (Malibu, CA)
Assignee: John Wayne Cancer Institute (Santa Monica, CA)
Application Number:08/462,106
Patent Claims:see list of patent claims

Details for Patent 6,218,166

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Organon Usa Inc. TICE BCG bacillus calmette-guerin POWDER, FOR SUSPENSION 102821 1 1990-08-24   Start Trial John Wayne Cancer Institute (Santa Monica, CA) 2018-04-17 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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