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Last Updated: October 1, 2020

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Patent: 6,214,331

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Summary for Patent: 6,214,331
Title: Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
Abstract:The invention is a process for the preparation of crosslinked water-swellable polymer particles. First, an aqueous polymer solution containing a water-soluble polymer having at least one functional group or charge, is combined with aqueous medium. The aqueous polymer solution is then mixed under moderate agitation with an oil medium and an emulsifier to form an emulsion of droplets of the water-soluble polymer. A crosslinking agent capable of crosslinking the functional groups and/or charges in the water-soluble polymer is then added to the emulsion to form crosslinked water-swellable polymer particles. The invention also includes the particles formed by the process and aqueous dispersions containing the particles which are useful for administering to an individual. The particles of the invention are useful for implantation, soft tissue augmentation, and scaffolding to promote cell growth.
Inventor(s): Vanderhoff; John W. (Bethlehem, PA), Lu; Cheng Xun (Somerset, NJ), Lee; Clarence C. (Lilburn, GA), Tsai; Chi-Chun (Lawrenceville, GA)
Assignee: C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA)
Application Number:08/989,888
Patent Claims:see list of patent claims

Details for Patent 6,214,331

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bpl ALBUMINEX albumin human SOLUTION 125644 1 2020-05-27   Start Trial C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA) 2015-06-06 search
Kedrion S.p.a KEDBUMIN albumin (human) INJECTION, SOLUTION 125384 1 2011-09-15   Start Trial C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA) 2015-06-06 search
Octapharma Usa Inc ALBUMIN (HUMAN) albumin human SOLUTION 125154 1 2006-10-17   Start Trial C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA) 2015-06-06 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA) 2015-06-06 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial C. R. Bard, Inc. (Murray Hill, NJ) Lehigh University (Bethlehem, PA) 2015-06-06 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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