➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Johnson and Johnson
McKinsey
Mallinckrodt
Harvard Business School
Moodys
McKesson

Last Updated: October 18, 2021

DrugPatentWatch Database Preview

Patent: 6,194,176

➤ Get the DrugPatentWatch Daily Briefing

« Back to Dashboard

Summary for Patent: 6,194,176
Title: Recombinant expression of proteins from secretory cell lines
Abstract:The present invention a provides methods for production of heterologous polypeptides using a variety recombinantly engineered secretory cell lines. The common feature of these cell lines is the absence of expression of at least one endogenous polypeptide. The host cell machinery normally used to produce the endogenous polypeptide is then usurped for the purpose of making the heterologous polypeptide. Also described are methods engineering cells for high level expression, methods of large scale protein production, and methods for treatment of disease in vivo using viral delivery systems and recombinant cell lines.
Inventor(s): Newgard; Christopher B. (Dallas, TX), Halban; Philippe (Geneva, CH), Normington; Karl D. (Dallas, TX), Clark; Samuel A. (Rockwell, TX), Thigpen; Anice E. (Dallas, TX), Quaade; Christian (Dallas, TX), Kruse; Fred (Dallas, TX)
Assignee: Board of Regents, The University of Texas System (Austin, TX) Betagene, Inc. (Dallas, TX)
Application Number:08/785,271
Patent Claims:see list of patent claims

Details for Patent 6,194,176

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 2015-01-23 ⤷  Free Forever Trial Board of Regents, The University of Texas System (Austin, TX) Betagene, Inc. (Dallas, TX) 2016-01-19 RX Orphan search
Schering INTRON A interferon alfa-2b VIAL 103132 1986-06-04 ⤷  Free Forever Trial Board of Regents, The University of Texas System (Austin, TX) Betagene, Inc. (Dallas, TX) 2016-01-19 RX search
Fresenius Kabi Usa CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017067 1973-03-05 ⤷  Free Forever Trial Board of Regents, The University of Texas System (Austin, TX) Betagene, Inc. (Dallas, TX) 2016-01-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

McKesson
AstraZeneca
Harvard Business School
Merck
Johnson and Johnson
Baxter

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.