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Last Updated: November 29, 2021

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Patent: 6,183,969

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Summary for Patent: 6,183,969
Title: Intron-based assay for detecting and characterizing chromosomal rearrangement
Abstract:An assay is provided for detecting and characterizing chromosomal rearrangements in eukaryotic cells by genetically engineering a eukaryotic cell to contain a selectable/counter-selectable marker gene with a site for generating a double strand break within an intron of the eukaryotic cell; generating the double strand break; detecting cells which repair the double strand break by chromosomal rearrangements; isolating DNA from the detected cells; and characterizing the chromosomal rearrangement as a nonhomologous translocation, inversion, deletion or insertion.
Inventor(s): Gabriel; Abram (Princeton, NJ)
Assignee: Rutgers, The State University of New Jersey (New Brunswick, NJ)
Application Number:09/293,569
Patent Claims:see list of patent claims

Details for Patent 6,183,969

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Try it Free 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Try it Free 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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