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Generated: September 22, 2019

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Patent: 6,165,993

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Summary for Patent: 6,165,993
Title: DNA vaccines against rotavirus infections
Abstract:This invention relates to methods of eliciting an immune response and/or protective immunity in a vertebrate by introducing into the vertebrate a DNA vaccine which consists essentially of DNA encoding an antigen or antigens, e.g., capsid proteins or polypeptides, of rotavirus. The uptake of the DNA vaccine by a host vertebrate results in the expression of the capsid protein, thereby eliciting humoral or cell-mediated immune responses, or both, which can provide protection against infection and/or prevent clinically significant rotavirus-caused disease. In addition, the invention demonstrates that an internal viral antigen provides protective immunity in a host. The host can be any vertebrate, including birds, piglets, and humans.
Inventor(s): Herrmann; John E. (Northborough, MA), Robinson; Harriet L. (Southborough, MA), Fynan; Ellen F. (Sterling, MA)
Assignee: University of Massachusetts Medical Center (Worcester, MA)
Application Number:09/233,813
Patent Claims:see list of patent claims

Details for Patent 6,165,993

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial University of Massachusetts Medical Center (Worcester, MA) 2012-03-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial University of Massachusetts Medical Center (Worcester, MA) 2012-03-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial University of Massachusetts Medical Center (Worcester, MA) 2012-03-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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