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Generated: August 21, 2019

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Patent: 6,165,715

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Summary for Patent: 6,165,715
Title: Expression systems
Abstract:The invention relates to new expression systems and in particular to an expression system in which a gene of interest is expressed at an optimal level. The invention provides a recombinant expression vector comprising a gene of interest and a selectable marker gene, wherein the selectable marker gene is arranged downstream of the gene of interest and a stop codon associated with the gene of interest is spaced from a start codon of said selectable marker gene at a distance which is sufficient to ensure that translation reinitiation is required before said selectable marker protein is expressed from the corresponding mRNA. Examples of such expression systems are vector viral packaging cell lines and a number of preferred cell lines have been identified.
Inventor(s): Collins; Mary Katherine Levinge (London, GB), Weiss; Robin Anthony (London, GB), Takeuchi; Yasuhiro (London, GB), Cosset; Francois-Lois (Lyons, FR)
Assignee: Cancer Research Campaign Technology Limited (GB)
Application Number:09/011,745
Patent Claims:see list of patent claims

Details for Patent 6,165,715

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Try a Free Trial Cancer Research Campaign Technology Limited (GB) 2015-08-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Try a Free Trial Cancer Research Campaign Technology Limited (GB) 2015-08-23 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Try a Free Trial Cancer Research Campaign Technology Limited (GB) 2015-08-23 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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