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Last Updated: September 18, 2020

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Patent: 6,136,960

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Summary for Patent: 6,136,960
Title: Method for evaluation of the ratio of amounts of biomolecules or their sub-populations in a mixture
Abstract:The present invention is directed to a method of determining the ratio of the concentration or amounts of two or more chemical compounds and/or biopolymers, or of the relative amounts of sub-populations of closely structurally related compounds, in a multi-component mixture, extract, system, and the like using an analytical physicochemical process. The method is based on distribution of the components of the mixture (system, extract, etc.) between two or more immiscible phases and the subsequent determination of the total amounts (concentrations) of biopolymers (chemical compounds) or of the amounts (concentrations) of one or more component(s) or sub-populations of the system in the phases. The ratio between these concentrations is defined therein as the partition coefficient. The partition coefficient is used as a measure of the ratio of the amounts of two or more biopolymers (chemical compounds) or their sub-populations in a multi-component mixture (extract, system, etc.), when calibrated against a series of sample systems of the same type with varied ratios of components.
Inventor(s): Chait; Arnon (Bay Village, OH), Zaslavsky; Boris Y. (Solon, OH)
Assignee: Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH)
Application Number:09/135,751
Patent Claims:see list of patent claims

Details for Patent 6,136,960

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Grifols Usa, Llc PLASBUMIN albumin (human) SOLUTION 101138 1 1994-09-26   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
Baxalta Us Inc. FLEXBUMIN albumin human INJECTION, SOLUTION 101452 1 2014-07-31   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
Csl Behring Ag ALBURX albumin (human) SOLUTION 102366 1 2009-01-06   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
Grifols Usa, Llc ALBUTEIN albumin (human) INJECTION, SOLUTION 102478 1 2019-12-15   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
Grifols Usa, Llc HUMAN ALBUMIN GRIFOLS albumin (human) SOLUTION 103352 1 2003-06-11   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
Csl Behring Llc ALBUMINAR-25 albumin (human) SOLUTION 103955 1 2009-01-06   Start Trial Zaslavsky; Boris Y. (Solon, OH) Chait; Arnon (Bay Village, OH) 2016-04-19 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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