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Last Updated: December 2, 2021

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Patent: 6,130,090

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Summary for Patent: 6,130,090
Title: Methods of performing gene trapping in bacterial and bacteriophage-derived artificial chromosomes and use thereof
Abstract:A method of efficiently sequencing multiple exons from complex genomic DNAs is disclosed. The methodology includes the use of bacterial and bacteriophage-derived artificial chromosomes (BBPACs) in novel gene trapping protocols. Targeted gene trapping by homologous recombination, and random gene trapping with the use of a transposon system are exemplified. Included in the invention are methods of preparing a gene map from BBPAC contigs, the resulting gene maps, methods of constructing a cDNA library from BBPAC contigs, and the resulting cDNA libraries.
Inventor(s): Heintz; Nathaniel (Pelham Manor, NY), Jiang; Weining (New York, NY), Yang; Xiangdong W. (New York, NY)
Assignee: The Rockefeller University (New York, NY)
Application Number:09/007,206
Patent Claims:see list of patent claims

Details for Patent 6,130,090

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2017-06-23
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2017-06-23
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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