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Generated: August 24, 2019

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Patent: 6,121,021

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Summary for Patent: 6,121,021
Title: Constitutive expression of non-infectious HIV-like particles
Abstract:Non-infectious, non-replicating immunogenic HIV-like particles are produced by stable longn-term constitutive expression in mammalian cells by eliminating elements toxic to the mammalian cells. An expression vector contains a nucleic acid molecule comprising a modified HIV genome devoid of long terminal repeats and wherein Tat and vpr sequences are functionally disabled and a constitutive promoter operatively connected to the modified HIV genome for constitutive expression of the modified genome to produce the HIV-like particles.
Inventor(s): Rovinski; Benjamin (Thornhill, CA), Yao; Fei-Long (North York, CA), Cao; Shi Xian (Etobicoke, CA)
Assignee: Connaught Laboratories Limited (North York, CA)
Application Number:08/991,773
Patent Claims:see list of patent claims

Details for Patent 6,121,021

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Sign Up Connaught Laboratories Limited (North York, CA) 2037-11-19 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Sign Up Connaught Laboratories Limited (North York, CA) 2037-11-19 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Sign Up Connaught Laboratories Limited (North York, CA) 2037-11-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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