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Last Updated: January 26, 2020

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Patent: 6,090,920

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Summary for Patent: 6,090,920
Title: Aminoterminal propeptides of typed 1 procollagen
Abstract:Aminoterminal propeptide of type I procollagen exists in serum in two forms: classical type I procollagen which is a heterotrimer containing two pro .alpha.1-chains and one pro .alpha.2-chain of type I procollagen, and an .alpha.1-homotrimer type I procollagen containing three identical pro .alpha.1-chains. These intact, trimeric aminoterminal propeptides may be isolated without the use of proteolytic enzymes and the resultant propeptides may be used to prepare antibodies specific for the intact trimeric propeptide, having no affinity for the monomeric form of the propeptide. Such antibodies are useful in methods of assaying intact trimeric aminoterminal propeptide of type I procollagen in serum, without false information resulting from inadvertent assay of the monomeric form of the propeptide.
Inventor(s): Risteli; Juha (Oulu, FI), Risteli; Leila (Oulu, FI), Melkko; Jukka (Oulu, FI), Kauppila; Saila (Oulu, FI)
Assignee: Orion-Yhtyma Oy (FI)
Application Number:09/033,311
Patent Claims:see list of patent claims

Details for Patent 6,090,920

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Orion-Yhtyma Oy (FI) 2015-04-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving leading biopharmaceutical companies globally:

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